Work touches every individual, all generations and peoples, there is no man who has not worked in his life without getting tired of it. I believe that prayer goes hand in hand with work as an important feature of the Catholic faith, as many saints throughout history have testified to us, and about which the Church's Magisterium, Pope Leo XIII, John Paul II and others write. With this paper, I do not intend to go into too great depths of human labor issues, but I want to give a closer insight into the topic that touches all spheres of human life: human identity, family, mutual relations of colleagues at work, vacation, and employer-employee relations. Through work, man continues God's creative work in the world, so it is prayer that consecrates work and brings man closer to his Creator. Saint Josemaría Escrivá preached about consecration through work in a special way, for which holiness is reserved not only for people from the clerical class but also for the laity. For these reasons, he founded Opus Dei with which he wants to bring the Good News to the student at his desk, the factory worker and the housewife in household chores, and to teach the faithful that they can do the work of God. One cannot speak about work without mentioning Karl Marx, the founder of Marxist philosophy, who in his work views man as an estrangement commodity, a lost person deprived of all meaning in life. Religion is considered an opium for the people that distracts man from reality, while Marxism wants to reduce him to mere matter.